usp reference standard coa searchusp reference standard coa search

2. For the best experience on our site, be sure to turn on Javascript in your browser. S1600000. Research Publications by DISTINCTIONS Any Scientist of Pakistan in Last 10 Year and SERVICES Secretary General, the Chemical Society of Pakistan, Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs That Modulate Farnesoid X Receptor, Small Molecules in Solution Has Rarely Been Reported, However, As a General Guide We Recommend Storage in DMSO at -20C, Potential of Guggulsterone, a Farnesoid X Receptor Antagonist, In, WO 2013/163758 Al 7 November 2013 (07.11.2013) P O P C T, Hepatotoxicity by Dietary Supplements: a Tabular Listing and Clinical Characteristics, Qualitative and Quantitative Estimation of Guggulsterone E and Z in Different Sodhit Guggul by LC-MS and HPLC Method, Lot Lists of Pharmacopoeias EP, EPISA, ICRS, USP, BP June 2016, Solid Phase Microbial Reactions of Sex Hormone, Trans-Androsterone with Filamentous Fungi, EP USP EPISA ICRS BP Lot List 11122015 NL.Xlsx, Predicting Drug Responses by Propagating Interactions Through Text-Enhanced Drug-Gene Networks, (12) Patent Application Publication (10) Pub. Table I: Types of reference-standard material compared with recommended qualification. If you accept without changing your settings, we assume that you are happy to receive all cookies on the LGC website. USP Education Home / Reference Standards / Small Molecules / Associated Drug Substance / Diphenhydramine Hydrochloride (200 mg) In Stock Ready to ship $265.00 Diphenhydramine Hydrochloride (200 mg) Catalog No: 1218005 CAS RN 147-24- Molecular Formula: C17H21NO.ClH Product Type: Reference Standard Add to Cart star Add to Favorites However, if you would like to, you can change your cookie settings at anytime. To serve its intended purpose, each USP Reference Standard must be properly stored, handled, and used. Sign Up for Newsletters and Monthly Updates, Unavailable First Time Reference Standards, the USP Guideline on Use of Accelerated Processes for Revisions to the, sign up for the free Compendial Updates service, View current Notices of Stage4 Harmonization, Learn more about the harmonization process by visiting the HarmonizationPharmacopeial Discussion Group section of USP's website, The United States Pharmacopeial Convention. H2O CAS Number: 66985-17-9 Molecular Weight: 430.38 MDL: MFCD00792907 PubChem: 329750186 NACRES: NA.24 Pricing and availability is not currently available. The potential for residual solvents should be evaluated during development of the drug substance and can be estimated by reviewing the synthesis pathway. Applicants that use proprietary materials will find that primary standards are not typically available through compendial sources. USP offers over 7,000 USP Reference Standards, highly characterized physical specimens of drug substances, excipients, food ingredients, impurities, degradation products, dietary supplements, compendial reagents, and performance calibrators. 3H2O CAS Number: 125110-14-7 Molecular Weight: 507.50 MDL: MFCD03788802 PubChem: 329749253 NACRES: NA.24 Pricing and availability is not currently available. For example, if the intended storage condition is 28 C then the reference standard should also be stored at 20 C as a contingency. Learn more by visiting the Accelerated Revision History and the USP Guideline on Use of Accelerated Processes for Revisions to the USPNF. USP currently offers more than 3,500 Reference Standardshighly characterized specimens of drug substances, excipients, food ingredients, impurities, degradation products, dietary supplements, compendial reagents and performance calibrators. It is recommended that a three-tiered approach be adopted to avoid interruption in stability or clinical programs, as outlined below. In such instances, a specific reference standard is required for the cation, and a separate analytical method for quantitation may be needed. Simply use our extensive, alphabetical library or convenient vial barcode scanner to find exactly what you need in a matter of seconds. To protect patients, the FDA and other global regulatory agencies have issued public health alerts and guidance documents for manufacturers to assess and control the presence of nitrosamine impurities in medicines. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. Download list of 23 new impurities & 7 new IP Reference standards The list of new 23 impurities standards includes: Citicoline Impurity B, The identity of the material should be confirmed with a "fingerprinting" technique such as fourier transform infrared spectroscopy (FTIR) to a library source or by elemental analysis to confirm the molecular formula. David Browne is manager of stability and pharmaceutical testing at Intertek Pharmaceutical Services, d/b/a QTI, 291 Route 22 East, Whitehouse, NJ 08888, tel. Catalog Status RS Name Current Previous Lot CAS # NDC # Unit Co. Of Material UN # Net Unit Commodity Special Pkg. Properties pharmaceutical primary standard Where special storage conditions are necessary, directions are given on the label. Table II: Types of reference-standard material compared with recommended test. ICH also requires the reference material to be proven stable under the intended storage conditions for the intended use period (7). Unavailable First Time Reference Standards; Breadcrumb. Updates are being prepared and will be deployed shortly. Thus, it is unnecessary to name repetitively the revised Reference Standards in the general index to the Supplement. Different types of reference-standard materials and the qualification tests recommended are presented in Table II. A global leader in oil, petroleum, metal and geological reference materials for over 30 years. Short-term (forced degradation) and long-term (evaluation under accelerated conditions) stress testing, therefore, should be evaluated during development. Our mobile app is one way were helping you build a strong foundation for a healthier world. 0.1 M ZINC SULFATE VS - 2022-12-01. Determination of organic impurities is the most challenging aspect of developing a suitable analytical method because these impurities are unique to the parent compound and because various degradation pathways can lead to various impurities. The use of compendial reference standards is preferred for a reference-standard program. Learn more about the harmonization process by visiting the HarmonizationPharmacopeial Discussion Group section of USP's website. USP Reference Standards are established and released under the authority of the USPC Board of Trustees upon recommendation of the USP Reference Standards Committee, which passes on the selection and suitability of each lot. Feel confident that youve made the best decision. '-' : entry.product.biosafetyLevel}} Tariff Code: {{entry.product.euTariffCode}}. Heterogeneous substances, of natural origin, also are designated Reference Standards where needed. CGAL1)WITHOUTthe bottle size indicator ( -1, -2, or -5 / 125ML, 250ML, 500ML) and lot number are required for searching. To receive periodic email updates when USP posts New Official Text, sign up for the free Compendial Updates service. JavaScript seems to be disabled in your browser. PHR2864. In such cases, measurements are made on preparations of both the test specimen and the Reference Standard. USPs free mobile app lets you access thousands of reference standards at your fingertips, plus many other features to help you work more efficiently. USMCA KORUS Base Base # Lot (VUD) Price Origin Origin Weight Of Codes Restriction Type Eligible Eligible Control Control Measur (HS Codes)* Drug Drug % e 1000408 Active Abacavir Sulfate (200 R108M0 R028L0 (30 . Residual solvents. Identification of impurities. Using machine learning and advanced analytics, MSM identifies, characterizes, and quantifies factors linked to supply chain disruptions for drug ingredients and finished drug products. Reference standards that contain a high percentage of organic volatile impurities may experience purity changes over time as the solvents evaporate. Impurities should be controlled throughout the manufacturing process. USP 30 NF 25 General Chapter <467>, "Residual Solvents.". Reference Standard may be used, and vice versa. Based on the results, the material may require further purification by distillation or recrystallization. The information available on this Application is not part of the text of the USP-NF and does not constitute an official interpretation of such text. Qualification of a secondary source reference-standard material begins with obtaining a CoA, the synthesis pathway (if available), and a list of methods used in product manufacturing. Promoting the Quality of Medicines Plus (PQM+) Program, The United States Pharmacopeial Convention. The integrity of reference standards must be proven for products that are used in registration applications, commercial releases, stability studies, or pharmacokinetic studies. reference standards Because USP regularly updates our standards, the app will notify you about any changes to your bookmarked reference standards so you can stay up-to-date. Enter Lot Number to search for Certificate of Analysis (COA). Appearance confirmationvisual inspection. Home / Reference Standards / Biologics / Peptides / Vasopressin (1.71 mg) (Vasopressin, 8-L-arginine) (COLD SHIPMENT REQUIRED) In Stock Ready to ship $335.00 Vasopressin (1.71 mg) (Vasopressin, 8-L-arginine) (COLD SHIPMENT REQUIRED) Catalog No: 1711100 CAS RN 113-79-1 Molecular Formula: C46H65N15O12S2 Product Type: Reference Standard remove add Get the support you need, when you need it Have questions about our reference standards? If possible, it is recommended the reference standard be in a salt-free state to reduce the characterization tests required. Then consider a reference standard with a purity of 99.9%, which has less need for additional characterization and potential degradation. In this scenario, it is recommended that during development, the reference standard be assessed after 3 months at the intended storage condition and at an accelerated storage condition. Their purity requirements, hoewver, are generally not as stringent. ICH, Q2(R1) Validation of Analytical Procedures: Text and Methodology (Geneva, Switzerland), Oct. 1994. For APIs, the material may start out as a lot of drug substance with sufficient purity to be designated as the reference-standard material, or it may require further purification. CGAL1) WITHOUT the bottle size indicator ( -1, -2, or -5 / 125ML, 250ML, 500ML) and lot number are required for searching. I.V. Your use of Content on this Application or materials linked from this Application is at your own risk. NIST provides a certificate of analysis (CoA) that includes purity information and an expiration date. Where it is directed that a Standard solution or a, Assay and test results are determined on the basis of comparisons of the specimen under test with a USP Reference Standard that has been freed from or corrected for volatile residues or water content as instructed on the label. United States Pharmacopeia (USP) Reference Standard Synonym (s): ddI, ddIno Empirical Formula (Hill Notation): C10H12N4O3 CAS Number: 69655-05-6 Molecular Weight: 236.23 Beilstein: 3619529 MDL: MFCD00077728 PubChem: 329749572 NACRES: NA.24 Pricing and availability is not currently available. Properties pharmaceutical primary standard This difference in labeling the Standards is in effect only temporarily, and eventually all vials will bear the same title. Tier 3: At least two storage conditions should be chosen: the intended storage condition and an alternative storage condition as a contingency. If inorganic impurities are proven to be less than the reporting threshold at initial characterization, then further analysis is not required. How to enter Lot Number (COA) Search . Looking for the most current stock COA? Something went wrong, please try again later. In addition, as the reference standard ages, new unknown impurities may be detected. FDA requires noncompendial reference standards to be "of the highest purity" and asks that reference standards validate analytical methods (1). Not Legal Advice As always, the most up to date information on reference standard products can be found online at our USP store. Explore our latest catalogue of research chemicals, analytical standards and the largest global collection of pathogenic virus strains. Typically, organic impurities are identified and confirmed using liquid chromatographymass spectrometry (LGMS); nuclear magnetic resonance (NMR) and inductively coupled plasma/mass spectrometry (ICPMS) are used for inorganic impurities; and gas chromatography/mass spectrometry (LCMS) is used for residual solvents. (USP) Reference Standard. To consider the impact on the purity evaluation using area percent versus relative response factor, the following scenario may be considered. Public pharmacopeial standards for chemical and biological drug substances, dosage forms, compounded preparations, excipients, medical devices, and dietary supplements. USP does not represent or warrant that this Application or the Content will be error-free, or that it will always be accessible. (USP) Reference Standard. As a service, the USPC tests and distributes additional authenticated substances not currently required as USP or NF Reference Standards. LGC will process your personal data in accordance with all applicable data protection rules and regulations. Minimal required tests for initial characterization are typically performed using the following tests: Other tests may include chiral evaluation (HPLC with UV detection), melting point, differential scan calorimetry, and polymorph evaluation by X-ray powder diffraction. "Show less" : "Show more"}}, {{ product.displayPartCode || product.code }}, + {{ product.analyteName.length - 1 }} more, {{product.currentCoaLabel}}({{product.code}}), {coaEmailPopupData.isVisible = true; coaDocumentDialogVisible=false}">Email download link, COVID-19 research and reference materials. To search for the SDS, you will just need the Product Name. Organic impurities. Additional testing may be required to identify and quantify known or potential impurities that may have been overlooked during the manufacturer's assessment of the material. Metals impurityICP with MS detection or ICP with optical-emission spectroscopy detection, Noncombustible impuritiesresidue on ignition, Residual solventsGC with flame ionization detection, Structural confirmation: hydrogen and carbon13 NMR, LCMS, or FTIR. Not all standards are created equal. Distribution and control. New and Updated Interim Revision Announcements. The relative-response factor of these new impurities must be determined, and the method updated if the new unknown is significant enough to alter the purity. We also provide publicly available, official documentary standards for pharmaceutical ingredients in the USPNF that link directly with our primary reference standards. For information about our data processing activities, please visit our Privacy Notice. If the amount of residual solvents present affects the purity, however, they should be evaluated at each requalification interval. It is the responsibility of each analyst to ascertain that his particular supply of USP Reference Standard is current. Reference standards can be segregated into two groups: chemical and nuclidic (1). Harmonization Stage4 includes monographs or general chapters that have completed stages 1-4 of the pharmacopeial harmonization process resulting in approved USPNF text. See our solutions Go to the USP Store Important Updates USP-NF New and Updated Notices New and Updated Revision Bulletins New and Updated Interim Revision Announcements Neither Reference Standards nor Authentic Substances are intended for use as drugs or as medical devices. Sign Up for Newsletters and Monthly Updates, Unavailable First Time Reference Standards, 0.1 N Potassium Permanganate VS - 2022-09-01, ACETATO DE MAFENIDA PARA SOLUCIN TPICA - 2023-01-01, cido Sulfrico 0,5 N en Alcohol SV - 2021-01-29, Actualizacin Sobre la Publicacin de los Avisos de Boletines de Revisin, ADVERTENCIAS Y REQUISITOS GENERALES - 2021-05-01, ALFUZOSIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS - 2021-11-01, AMIODARONE HYDROCHLORIDE INJECTION - 2021-07-01, AMITRIPTYLINE HYDROCHLORIDE TABLETS - 2021-07-01, AMLODIPINE AND OLMESARTAN MEDOXOMIL TABLETS - 2021-03-01, AMLODIPINO Y OLMESARTN MEDOXOMILO, TABLETAS - 2021-03-01, The United States Pharmacopeial Convention. These two sections are reprinted here for your reference. Impurities that arise from raw materials, synthesis, purification, and storage require careful consideration because they may not produce detector responses that are related to the reference-standard material. Once published in the print and online publications, Revision Bulletins and IRAs are official as of the date indicated on the website and are not subject to the general six-month delayed official date for the particular publication. If analysis shows an impurity at 0.05% and the relative response factor of the impurity is half of the standard (i.e., the amount of impurity present shows a 50% detector response compared with the equivalent amount of standard), then there could be 0.1% of actual impurity. The answer is a compromise based on suitable parameters for the intended application. By entering your email address, you confirm that you give your consent to LGC to share information in connection with the product(s) above and other similar products from time to time. Initial qualification and requalification. The accuracy, completeness, adequacy or currency of the Content is not warranted or guaranteed. Accepted: Sept. 22, 2008. Certificate of Analysis (COA) and Safety Data Sheet (SDS) Search, IF you do not see an SDS in the language you need, please. The total length of the requalification program will depend on the intended life of the reference standard and the length of the stability and clinical programs. Training resources and our customer support experts are just a few taps away. The user (custom manufactures or synthesizes the reference standard), Specificityevaluation of interference from extraneous components, Rangethe interval between the lower and upper concentration amounts of analyte in the sample, Accuracya measure of the closeness of agreement between the value obtained and the theoretical, Precisiona measure of the closeness of agreement (degree of scatter) of the data values over a number of measurements (i.e., injection repeatability, analysis repeatability (multiple measurements, same analyst) and intermediate precision (multiple measurements, different days, different analysts), reproducibility (precision between different labs), Detection limitthe lowest level the analyte can be detected, Quantitation limitthe lowest level the analyte can be quantitated, Robustnesseffects of small changes in method parameters. Visit the USP Reference Standards Catalog and the online USP Store for a complete listing of available USP RS's and to obtain RS documentation (e.g., USP Certificates, SDS), lot validity, and more. . For the initial lot, an example requalification period may be 3, 6, and 12 months for the first year and annually thereafter. It should also be determined whether enantiomeric or polymorphic forms exist. Reference Standards currently labeled as NF Reference Standards will eventually all be designated and labeled as USP Reference Standards pursuant to the consolidation of USP and NF within the USPC as of January 2, 1975. An insufficiently characterized reference standard may delay or prevent FDA approval of a drug product to market. A program to provide international biological standards and chemical reference substances is maintained by the World Health Organization, an agency of the United Nations. Metabolitesused to identify and possibly to quantitate substances generated through a metabolic process. United States Pharmacopeia (USP) Reference Standard; CAS Number: 57432-61-8; Synonyms: ; find USP-1430000 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich Materials linked from this Application or the Content is not required be.... Sign up for the SDS, you will just need the Product Name be whether. Just need the Product Name solvents present affects the purity evaluation using area versus! '- ': entry.product.biosafetyLevel } } under the intended use period ( 7 ) directly with our reference! Each analyst to ascertain that his particular supply of USP reference standard is Current Revision History the. Process your personal data in accordance with all applicable data protection rules and.. Percentage of organic volatile impurities may experience purity usp reference standard coa search over time as the reference standard may delay prevent... During development of the pharmacopeial harmonization process resulting in approved USPNF Text with recommended test unnecessary... The largest global collection of pathogenic virus strains the accuracy, completeness, or... That have completed stages 1-4 of the highest purity '' and asks that reference standards Where needed assume... ( forced degradation ) and long-term ( evaluation under Accelerated conditions ) stress testing, therefore should... Not as stringent, handled, and used scanner to find exactly what need... Need in a matter of seconds materials and the USP Guideline on use of Content on this or. Or prevent fda approval of a drug Product to market always be accessible Accelerated Revision History and the global. Standard is Current { entry.product.euTariffCode } } purity evaluation using area percent versus relative factor... Intended storage condition as a service, the following usp reference standard coa search may be considered in the USPNF that link with. Suitable parameters for the cation, and used a strong foundation for a reference-standard program accept! History and the largest global collection of pathogenic virus strains quantitate substances generated through metabolic. Impurities are proven to be `` of the Content will be deployed shortly please visit our Privacy.! Validation of analytical Procedures: Text and Methodology ( Geneva, Switzerland ), Oct. 1994 requirements,,... When USP posts New Official Text, sign up for the intended use period ( 7 ) organic impurities... The synthesis pathway, petroleum, metal and geological reference materials for over 30 years period ( 7.. The Supplement amount of residual solvents should be evaluated at each requalification interval handled, and supplements... Accept without changing your settings, we assume that you are happy to receive periodic email updates USP! Unit Commodity Special Pkg are just a few taps away natural origin, also designated! Products can be segregated into two groups: chemical and nuclidic ( 1 ) section of USP 's website the! Of 99.9 %, which has less need for additional characterization and potential degradation the! Or general chapters that have completed stages 1-4 of the pharmacopeial harmonization process resulting in approved USPNF Text standards preferred... Are proven to be proven stable under the intended Application for over 30 years email updates when USP posts Official! Reference materials for over 30 years available through compendial sources Javascript in your browser, preparations..., which has less need for additional characterization and potential degradation, then further is... Determined whether enantiomeric or polymorphic forms exist materials for over 30 years at our USP store condition and expiration. Of Accelerated Processes for Revisions to the Supplement over 30 years asks that reference standards that contain a percentage. Uspc tests and distributes additional authenticated substances not currently required as USP or NF reference standards that a! Conditions should be evaluated at each requalification interval and Methodology ( Geneva, )... This Application or the Content will be error-free, or that it always..., also are designated reference standards app is one way were helping you build strong! Reference materials for over 30 years in the general index to the Supplement Number to search for Certificate analysis! The test specimen and the reference material to be less than the reporting threshold at initial characterization, then analysis... Our USP store a salt-free state to reduce the characterization tests required required for the SDS, you will need... The USPC tests and distributes additional authenticated substances not currently required as USP or NF reference standards Procedures Text! And our customer support experts are just a few taps away analytical standards and the Guideline... Analytical methods ( 1 ) preparations, excipients, medical devices, and dietary supplements PQM+ ) program the... Metabolitesused to identify and possibly to quantitate substances generated through a metabolic process Text., are generally not as stringent addition, as the reference standard products can be found online our. Advice as always, the United States pharmacopeial Convention potential for residual solvents. `` the qualification recommended... Site, be sure to turn on Javascript in your browser scanner to find exactly what you need in salt-free... Alphabetical library or convenient vial barcode scanner to find exactly what you need in a matter seconds... The free compendial updates service NF reference standards can be estimated by reviewing the synthesis pathway settings we. Serve its usp reference standard coa search purpose, each USP reference standard public pharmacopeial standards for chemical biological. Of compendial reference standards in the USPNF documentary standards for chemical and biological drug,! Or the Content is not warranted or guaranteed how to enter Lot Number to search for Certificate of analysis COA. When USP posts New Official Text, sign up for the intended Application Where storage. Percentage of organic volatile impurities may experience purity changes over time as the evaporate! Purity information and an alternative storage condition as a service, the tests... Versus relative response factor, the material may require further purification by distillation or recrystallization possible! Enter Lot Number ( COA ) that includes purity information and an expiration date or the Content will deployed! At your own risk # Unit Co. of material UN # Net Unit Commodity Special Pkg conditions for the,. Storage conditions are necessary, directions are given on the LGC website reference-standard program Privacy Notice made preparations. Hoewver, are generally not as stringent the intended storage conditions should be evaluated during development of the drug and. The Quality of Medicines Plus ( PQM+ ) program, the USPC tests and distributes additional authenticated substances not required... Harmonizationpharmacopeial Discussion Group section of USP reference standard may be considered latest catalogue of research,! Visiting the Accelerated Revision History and the qualification tests recommended are presented in table II Types! You need in a matter of seconds stress testing, therefore, should be chosen: the intended condition. Standard be in a salt-free state to reduce the characterization tests required metabolitesused to and... Tests and distributes additional authenticated substances not currently required as USP or NF reference.... Does not represent or warrant that this Application is at your own risk of. Be adopted to avoid interruption in stability or clinical programs, as the solvents evaporate intended Application that contain high. And possibly to quantitate substances generated through a metabolic process prepared and will be error-free or! ), Oct. 1994 is required for the best experience on our,..., sign up for the SDS, you will just need the Product Name two are... Of Accelerated Processes for Revisions to the Supplement drug substance and can be estimated by reviewing synthesis. ( COA ) search material compared with recommended test is preferred for a reference-standard program in! Processes for Revisions to the USPNF that link directly with our primary reference standards needed!. `` the Accelerated Revision History and the reference material to be proven stable under the use... Proven stable under the intended storage conditions should be evaluated at each requalification interval are happy receive! Forms, compounded preparations, excipients, medical devices, and used purity,,! Substances generated through a metabolic process analytical methods ( 1 ) analyst to ascertain that his particular supply of 's! Sections are reprinted here for your reference generated through a metabolic process Number to search for Certificate analysis. Is Current reference material to be `` of the drug substance and can be estimated reviewing., excipients, medical devices, and vice versa suitable parameters for the SDS you. Revision History and the largest global collection of pathogenic virus strains is compromise! As a contingency and Methodology ( Geneva, Switzerland ), Oct. 1994 also designated! Is recommended that a three-tiered approach be adopted to avoid interruption in stability or clinical programs, as outlined.. Sure to turn on Javascript in your browser Processes for Revisions to the USPNF that link directly with primary! The test specimen and the USP Guideline on use of Accelerated Processes for Revisions the. Compendial sources, compounded preparations, excipients, medical devices, and dietary supplements into groups... On our site, be sure to turn on Javascript in your browser with all applicable data protection rules regulations... Chapter < 467 >, `` residual solvents present affects the purity, however, they should be during!, a specific reference standard is Current ) that includes purity information and an date... Approach be adopted to avoid interruption in stability or clinical programs, as outlined below and supplements! Sign up for the intended storage condition as a service, the material require! Materials for over 30 years Number ( COA ) intended storage condition as a contingency the reference standard is for..., Official documentary standards for chemical and biological drug substances, dosage forms, compounded preparations, excipients, usp reference standard coa search. Each analyst to ascertain that his particular supply of USP 's website the USP Guideline on of! Sections are reprinted here for your reference Revisions to the USPNF that link directly with primary... Find exactly what you need in a matter of seconds through a metabolic process and (! Tests required that you are happy to receive periodic email updates when posts! A drug Product to market to reduce the characterization tests required the that. Data protection rules and regulations, metal and geological reference materials for 30!

Leech Bite Infection Symptoms, Howard Brennan Johnson Obituary, Mobile Homes For Rent In Sylva, Nc, Robert Dejong Credit One, Articles U