6. It is difficult to know what dose may be most useful in bone health (or if any dose is truly beneficial). After doing my research mostly on this site, I decided against it. (, Interestingly, a 2018 randomized controlled trial showed that adequate magnesium levels may be required to optimize Vitamin D status. Study: Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate, The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review, Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate, Calcium, vitamin D, vitamin K2, and magnesium supplementation and skeletal health, Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial, Cardiovascular Diseases and Fat Soluble Vitamins: Vitamin D and Vitamin K, Effect of supplementation with vitamins D3 and K2 on undercarboxylated osteocalcin and insulin serum levels in patients with type 2 diabetes mellitus: a randomized, double-blind, clinical trial, Vitamin D and Cardiovascular Disease: An Update, Psychobiotics, the Pharmacology of Probiotics, and Our Bodys Naturally Innate Pharmacy, The Potential Impact of Cholecystectomy on Drug and Xenobiotic Metabolism, and Liver Detoxification, Iron Deficiency Anemia and Detoxification. Oil-rich fish, such as salmon and herring, also contain vitamin D3. 200000ius per pill instead of 2000iu. Not sure if 400 too much or 300 not enough. That goes down by it's lonesome in the wee hours of the am. I take Vitamin D3 and K2 which helps the D3 to be absorbed. On the flip side it does not appear that vitamin K reduced the absorption of A, D and E. Confusion! Oil-rich fish, such as salmon and herring, also contain vitamin D3. by Dr. Ben Reebs | Jan 18, 2021 | Chronic Disease, Health, Minerals, Nutrition | 0 comments. Arterial calcification is an independent risk factor for cardiovascular disease, researchers noted. Vitamin K (phytonadione) starts working in six to 10 hours and reaches maximum effect in 24 to 48 hours (one to two days). What say you? Tablets and capsules don't contain any fat so would need dietary fat to aid absorption and are best taken at opposite ends of the day with some form dietary fat, maybe take one with breakfast and one with evening meal. Theres also MK-5, MK-8, and MK-9 however its not widely used as a supplement and theres more research needed. If you take 1,000 mg of calcium a day, split it into two or more doses over the day. Can anyone tell me what this is and what the difference between the two are? These findings indicate that genetic predisposition to higher circulating vitamin K1 levels is associated with an increased risk of large artery atherosclerotic stroke. Once you have been taking vitamin D for awhile, you should have your serum levels tested. The studies we have generally make the assumption that timing doesn't matter and blood 25(OH)D levels are the only interesting variable. Nothing on this website constitutes the practice of medicine, nor can it be used to treat or diagnose any health issue or concern. Taking Magnesium helps with D3 absorption. At the same time I also don't believe that any problems are going to arise from Vitamin C supplementation either alone or in combination with D3 & K2. I thought the menaquinone 4 version was the correct one to get. It must have, but by how much, and how fast? Natto. Musculoskeletal causes of difficulty walking Broken bones and soft tissues injuries, including sprains, strains and tendonitis. More specifically, researchers suggest taking vitamin D at the same time you eat foods that are high in fat. As a result I have decided to take MK4 (along with D3 etc) and it would seem to be sensible to start at a low dose of MK4. This cookie is set by GDPR Cookie Consent plugin. December 31, 2021 by Marian. Taking a Vitamin D3 supplement without K2 can have disastrous effect, as Vitamin D creates need for Vitamin K2 in the body. If absorption is not ideal when these vitamins, are taken together, then why are these formulas made? I think it's a case of finding a personal routine that causes us the least worry, without too much inconvenience. Calcifediol gets produced in our liver from cholecalciferol. early signs of vitamin D overdose--weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting. (6). Most people wont experience any effects from too much vitamin K. Several vitamins can be dangerous when you take too much of them, but for most people, vitamin K isnt one of them. Vitamin A is also plausible but given that too much Vitamin A is bad (on average Vitamin A supplements increase the death rate) I wouldn't supplement it in a targeted way without blood tests. A cup of sliced avocado can give you up to 50 micrograms of vitamin K. One-half cup of stewed prunes nets you about 32 micrograms. A one-ounce portion (roughly a quarter cup) of raw . Can you please advise me which is the best form to take? 2. I also read they should be taken separately so they don't compete. vitamin K2 came highly recommended for osteoporosis, even so before taking it I researched it thoroughly and everywhere they said vitamin K2 is beneficial for osteoporosis and the heart New comments cannot be posted and votes cannot be cast. Also, magnesium deficiency can negatively impact bone and muscle health. When you say you are low in Vitamin D, what are your values? Kind regards The research was done in Japan with a single 1.5 mg dose of MK4 daily and they noted improvements similar to those gained on the 15 mg three times a day dose used in prior experiments. And a 2015 study shows that fat-soluble vitamin deficiency is also strongly associated with cardiovascular disease. Vitamin D promotes the production of vitamin K-dependent proteins, which require vitamin K for carboxylation in order to function properly. In 2006, study findings published in the Journal of the American Medical Association suggested that vitamin D3 helps in improving the symptoms of multiple sclerosis, which is a disabling disease of the central nervous system (brain and spinal cord). Well, when the chart is approximated, the average is ~50 pulses. The answer to this question depends on various factors. Any ideas on where to get this info? But if you mix it with green tea, black tea, or curcumin supplements, your body won't absorb the mineral. What is the , It raises the risk for heart disease, cancer, liver damage, and stroke. Peptic ulcer disease. Is there anyone out there with Factor V taking Vitamin K without problem, There has been discussion of Vitamin D or calcium possibly causing calcification of arteries. Active Comparator: interventional . The amounts of the other supplements you take are generally safe and are at doses which may be helpful -- depending . Hello. Creatine. How Vitamin D3 and K2 Work Together. Does vitamin K thin or thicken your blood? Ive read on here to take them separately at different times of the day. Foremost, I generally recommend taking 320-500mcg per day of vitamin K2 in the form menaquinone K2-7 (320mcg + cofactors) or ADK Complete (5000 IU Vitamin A, 5000IU D3, and 500mcg K2-7) to support everyday wellness. The main consequence of vitamin D toxicity is a buildup of calcium in your blood (hypercalcemia), which can cause nausea and vomiting, weakness, and frequent urination. Always consult your physician first. (, D3 not only enhances intestinal calcium absorption, but it is also well established that Vitamin D3 is essential to immune function modulation. Myers said . I've been taking mine separately because I thought they might compete for absorption. Does vitamin K increase the risk of stroke? Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Intend to do another calcium score in 6 months time to see if there is a reduction. Taking Vitamin D3 with Vitamin K2 helps to ensure the calcium transported by the Vitamin D is absorbed by your bones where it's needed, rather than accumulating in deposits in your arteries. Anyone have anything to say about Vitamin K2, I was really excited to try Vitamin K2 in MK7 form after hearing such good things about it, but Im disappointed it gives me such bad reactions; irritability, brain fog, memory problems, depression, apathy, fatigue. St. John's wort can cause a buildup of serotonin in the body when taken with antidepressants. Call your doctor for medical advice about side effects. So when you take high doses of D like this, you should NOT be taking high doses of K, hence combination products would not be my recommendation for those of you taking a short-term high dose D supplement. http://blog.cholest, This is a new book by Kate Rheaume-Bleue, ND. While going out into the sun would also be a way to acquire Vitamin D3, it causes wrinkles in the face that while I dont try to minimize sun exposure I wont maximize it when I can get my Vitamin D3 through a cheap supplement. Sunshine vitamin D helps with calcium absorption, while vitamin K is important for blood clotting and preventing calcification of the arteries. I have not really been sure how much MK4 to take, so I just happened on 8 drops of the liquid MK4 (8 mcg) twice a day. The main symptom of vitamin K deficiency is bleeding (hemorrhage)into the skin (causing bruises), from the nose, from a wound, in the stomach, or in the intestine. Nitric oxide is a gas we make , Blood: THC from edibles can be detected for 3 to 4 days in blood. Gwern's meta-analysis on Vitamin D suggests that the existing academic publications suggest that this costs 0.33 years of life. Personally, I decided to consume every morning 10 000 IU of Vitamin D3 and 200 g of K2 (all-trans MK7) and believe that it's likely beneficial for many fellow rationalists who don't spend a lot of time exposing a lot of skin to the sun to take the same supplements. Going to start magnesium . As a certified health coach and yoga instructor, Sandra has a wealth of knowledge and experience in the fields of health and wellness. According to one study in 17 people, taking vitamin D with the largest meal of the day increased vitamin D blood levels by about 50% after just 2-3 months ( 7 ). In other words, this website and its content does not constitute professional medical advice. I'm not sure how much of a difference this makes though; taking it in the morning (with a not-fatty meal) is still enough to fix my deficiency. You can use the study as a second opinion to make health care decisions. Observational studies link low Vitamin K2 levels to blood vessel calcification with K2 being more important than K1. The cookie is used to store the user consent for the cookies in the category "Analytics". I have osteoporosis and my doctor is concerned about my taking Vitamin K, because it could thicken my blood. Vitamin K is an essential vitamin. That can lead to bone weakening ( osteoporosis) and increased fracture risk. This can result in serotonin syndrome, which causes side effects like anxiety, sweating, confusion, tremors, lack of coordination and an accelerated heart rate. I would ask a doctor or pharmacist. "Take Vitamin D3 and K2 separately Take your Vitamin K2 supplement with your dinner that includes dietary fat or at bedtime, 8 to 12 hours after you take your Vitamin D3. Get your levels tested. Well after being ill with some sort of virus from the Sunday before Christmas until the Sunday after New Year, I broke my right arm - Im only right handed! by Dr. Ben Reebs | Jun 28, 2021 | Chronic Disease, Diet, Digestion, Health, Inflammation, Microbiome, Nutrition. I just read some story in the news that says vitamin D3 supplements isn't helpful for bone health, I say BS. On the advice of others in this community, I have started taking Thorne Vit K2 MK4 drops twice a day. Upon exposure to sunlight, vitamin D is produced in the skin, then converted in the liver and kidney, respectively, to form D3. Our maximum daily dose was 5,000 IU. How much K2 do I need with D3? Here are two articles on BLOOD levels of magnesium. Could you add a follow-up comment regarding your D3 dosage: did switching from 5,000 UI to 10,000 UI daily increased your 25(OH)D level? K2, however, is mostly found in fermented foods and animal products, and also produced by our intestinal microflora. While there are some vitamins you should avoid taking together, there are others you'll want to combine in order to support absorption. This is not a complete list of side effects and others may occur. . Nearly 19 million Americans take fish oil supplements and some 37 percent of us take vitamin D. Many may be motivated by research that has suggested these pills . The reason that vitamin D3 is preferred over D2 is that D3 yields higher amounts of calcifediol as compared to the same dose of D2. Given that some supplements contain a mix of both forms its desirable to buy a MK-7 supplement that specifies that its all-trans (or 99% all-trans). Both calcifediol and calcitriol are used in many different pathways. Some people may also prefer taking them at certain times of day . Less serious side effects may be more likely, and you may have none at all. As to how much fat is ideal, I don't know but wish I could find an answer. One small 3.5 ounce packet should contain about 10g or 10,000 mcg of K2 in the MK7 form. This is a very safe dose as is documented on the website of the Vitamin D Council. Accordingly, subjects in the Rotterdam Study with the highest vitamin K2 intake consumed more total and saturated fats and also had lower total cholesterol values and higher levels of heart-protective HDL cholesterol. k2, menaquinone 7 and the bottle says it's good for the bone building process. Whats the difference in vitamin K and vitamin K2? Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Spinach and kale contain K1 and not K2. Supplementation reverses this. Has anyone had experience of reducing their calcium score by taking K2, as literature search is very encouraging. Deficiency is particularly common among breastfed infants. Common side effects of Citracal + D may include: an irregular heartbeat; weakness, drowsiness, headache; dry mouth, or a metallic taste in your mouth; or. You could also just send an email to their support and ask. I don't know if I need it, never took the blood test, I tried it based on all the artiles about how good it is and how most people are deficient in it. I dont ever take multivitamins and for some reason - well because I know you should take both K2 with D3 - I trusted that a D3/K2 combo would be ok. Silly me. It's in the scientific literature. Other problems from calcium and vitamin D deficiencies include: When taken together, vitamin C, vitamin D3, and zinc are a potent combination for delivering many health benefits, including immune support: Neuro-C Liposomal Vitamin C - advanced brain and immune defense. I used to take calcium-magnesium-zink supplement, not sure if it was durig the time I took D3. 9 of these (or an equivalent) a day; is 5mg a day (as suggested on the bottle) a complete waste of, listen to your body ,it is the best indicator of whats working for you & what isnt that Vitamin D toxicity at high doses is usually about K2 deficiency because both are needed in the same pathways and more K2 is needed when there's more Vitamin D. Vitamin D toxicity leads to hypercalcemia where there's too much Calcium in the blood. Vitamin D3 5000 - highly-potent and pure vitamin D3. 7. 2. VKDB was previously called hemorrhagic disease of the newborn. I had been taking vitamin K2 complex for 3 months and slowly developed a heart arrhythmia it became so bad I seriously consid, I have Factor V Leiden the type coming from one parent. Calcifediol moves some calcium from the bone to the blood and K2 is needed to put the calcium in the bones. Any formulation that includes D3 can be improved by K2," says Jrg Bttinghaus, Vice President Kappa Sales and Marketing. Never knew to take at diffrent times. Vitamin K2 takes it from there, directing that calcium into your bones. I often get asked, particularly by my patients who are already on or considering vitamin D3 supplementation, if they should take a form that includes vitamin K2. Taking both D3 and K2 together ensures that you're getting the most . Its recommended that males over 19 years old consume 120 mcg daily, and females over 19 years old consume 90 mcg daily. I'm German and I used to take 5000 IU vitamin D3 per day and got tested by my doctor and got a value of 33ng/ml. People with particular medical conditions may need more, as recommended by their doctor. This website and its content is not to be used in place of the information provided by your physician or healthcare professional. What is daily intake of Vit C for adults? Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. When should I take Vitamin D3 and K2? Boost your nutrition and get premium-quality vitamins D3 and K2 with Dr. Berg D3 & K2 Vitamin. If you're guilty of reaching for the fresh orange when you feel the first signs of a sniffle, Westra suggests doubling up on a B6 supplement. I often get asked, particularly by my patients who are already on or considering vitamin D3 supplementation, if they should take a form that includes vitamin K2. Mk-5, MK-8, and how fast K2 can have disastrous effect, as vitamin D Council much inconvenience the! 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