They also included problems with the esophagus, kidneys, nervous system, and abnormalities of the arms and legs. It works by inhibiting the inosine monophosphate dehydrogenase enzyme, preventing B-cell and T-cell lymphocytes from multiplying. For more information, see the CellCept for preventing organ rejection after a transplant section above. prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. Try to take your doses around the same time each day. You should avoid eating at least 1 hour before and 2 hours after taking CellCept. Sevelamer (Renvela, Renagel) is an example of a phosphate binder. This lowers your immune systems ability to attack the newly transplanted organ. However, be sure to take the dosage your doctor prescribes for you. Its also supported by additional data from use in children. However, clinical guidelines recommend using CellCept for lupus in adults who also have signs of kidney disease. This is because live vaccines generally require a healthy immune system to be effective. (For more information, see the Taking CellCept with food section below. Many of these side effects may go away within a few days or a couple of weeks. Its important to note that pregnancy registry data is self-reported, meaning the results are submitted by people taking the drug. It's important to keep taking mycophenolate even if it doesn't seem to be working at first. A boxed warning is the most serious warning from the FDA. increased risk of developing a food-related infection. are pregnant or plan to become pregnant. (For more information, see the Taking CellCept with food section below.). Both drugs were given with corticosteroids and cyclosporine (Neoral). It can be prescribed after a heart, kidney, or liver transplant with other immunosuppressant drugs. Having symptoms of organ rejection doesnt necessarily mean that your transplant has failed or that youll need another transplant. Call your doctor for medical advice about side effects. The CellCept dosage your doctor prescribes will depend on several factors. Whole grains. If you have questions about using CellCept to help prevent organ rejection, talk with your doctor. CellCept is also FDA-approved to help prevent organ rejection after a heart or liver transplant in adults and children ages 3 months and older. have Lesch-Nyhan syndrome, Kelley-Seegmiller syndrome, or another rare inherited deficiency hypoxanthine-guanine phosphoribosyl-transferase (HGPRT). (Cyclosporine is another antirejection drug.). These lists contain examples of serious side effects that can occur with CellCept, with Myfortic, or with both drugs (when taken individually). Treatment failure was defined as: The percentage of adults who experienced treatment failure varied depending on the dose being studied and the country where the study took place. To learn about using Prograf in children, talk with your childs doctor. People who take CellCept have a higher risk of getting skin cancer. Organ rejection can happen within days or weeks of the transplant. Your doctor will determine the best dosage to fit your needs. Taking CellCept with certain birth control pills can make these pills less effective. In addition to the use listed above, CellCept is also used off-label for other purposes at times. They may have a preference for one version or the other. Its prescribed to adults and children ages 3 months and older. (Skin spots may be discolored, scaly, or crusty.). They may be temporarily stored at temperatures of 59F to 86F (15C to 30C), such as when traveling. Take CellCept capsules, tablets and oral suspension on an empty stomach, unless your doctor tells you otherwise. Highly clinically significant. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Prograf (when taken individually). Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. Note: Some of the drugs listed here are used off-label to treat these specific conditions. Tell your doctor right away if you become pregnant while using CellCept. Foods that are raw or undercooked can contain germs that can cause food poisoning. . Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. The most common side effects of CellCept include: Side effects that can happen more often in children than in adults taking CellCept include: These are not all of the possible side effects of CellCept. CellCept is an antirejection drug that works by preventing immune cells from multiplying. This can lead to side effects from the chemotherapy drug. CellCept and Prograf are both brand-name drugs. You can also refrigerate the liquid at temperatures of 36F to 46F (2C to 8C). This is especially true for birth control pills that contain the active drug levonorgestrel. Specifically, CellCept is a type of immunosuppressant called an antirejection drug. To decrease your risk for skin cancer while using CellCept, you should limit your time spent in the sun. They can recommend ways to treat this side effect. View interaction reports for CellCept (mycophenolate mofetil) and the medicines listed below. There arent any herbs or supplements that have been specifically reported to interact with CellCept. To help prevent organ rejection, dont stop taking CellCept without first discussing the risks with your doctor. It isnt known how many people who used a placebo may have had depression. Phosphate binders are a group of drugs that are used to remove high levels of phosphate from your body. A change in your diet, medicine, or dosage may be necessary. The results showed that: The percentage of adults who had anemia after taking these drugs varied depending on the condition being treated. If taken with CellCept, these antacids can lower the amount of CellCept in your body. As a way of protecting your body, your immune system will try to get rid of it. CellCept is rapidly absorbed and converted to its active metabolite, mycophenolic acid. Both CellCept and Myfortic are available as tablets that you swallow. They can discuss ways to lower your risk. CellCept has a boxed warning for the risk of congenital anomalies and pregnancy loss. They can recommend a different treatment for your condition. These lists dont include all possible side effects that may occur with each drug. For more information about taking CellCept during pregnancy, see the CellCept and pregnancy section above. This extra fluid in your body can make it seem like youve gained weight. They can be prescribed to adults and children.. For more information, see the Boxed warnings section above.) (See the section right below to learn more about pregnancy registries.). A live vaccine contains a weakened form of the virus or bacteria that it helps prevent infection from. Its FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. Bactrim (sulfamethoxazole / trimethoprim), Email this report to a friend, doctor, or patient. Its also available as an intravenous (IV) infusion* (an injection into a vein over a period of time) thats given by your doctor. If you accidentally get the powder or oral suspension on the skin, wash the area well with soap and water. This means taking your dose either 1 hour before eating or 2 hours after eating. Brown rice. In most cases, you should take CellCept on an empty stomach (1 hour before eating or 2 hours after eating). It isnt known how many people may have had unexplained weight loss after using CellCept in clinical studies. CellCept and Prograf have some similar side effects and others that vary. CellCept contains the active ingredient mycophenolate mofetil. In addition, 23% to 27% of those who took part in pregnancy registries reported congenital anomalies after taking CellCept. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Both drugs are used with other immunosuppressants. This can include setting an alarm on your phone or downloading a reminder app. To learn about using Prograf in children, talk with your childs doctor. You should take CellCept according to your doctors or healthcare professionals instructions. CellCept is used with other medicines containing cyclosporine and corticosteroids. For more information about using CellCept to treat scleroderma, talk with your doctor. Therefore, this information was not gathered in a clinical study overseen by researchers. CellCept (mycophenolate mofetil), along with The result: too much drug in your body . If youre taking cholestyramine, be sure to tell your doctor before using CellCept. This form of Prograf is also typically taken twice per day. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Do not stop taking CellCept or change the dose unless your doctor tells you to. In clinical studies, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo (a treatment with no active drug) in adults whod had a heart transplant. CellCept is metabolized (broken down) in the body by a process called glucuronidation. CellCept and Myfortic have different FDA-approved uses, but theyre both used to help prevent organ rejection after kidney transplant. Call your healthcare provider right away. To learn more, see the CellCept use with other drugs section. How and where you store CellCept is slightly different for each form of the drug: If you no longer need to take CellCept capsules, tablets, or liquid and have leftover medication, its important to dispose of it safely. Of the total drug interactions, They make your body less likely to reject a transplanted organ. This can raise your risk for side effects. However, unexplained weight loss can also be a sign of cancer. They can discuss with you the risks and benefits of continuing your CellCept treatment. The CellCept infusion is given over a period of about 2 hours, twice per day. To keep the blood levels of mycophenolate the same, you should always take mycophenolate the same way, either with food or without food. *) Talk with your doctor about whether or not your condition is stable enough to take this drug with food. Mycophenolate comes as a capsule, a tablet, a delayed-release (releases the medication in the intestine) tablet, and a suspension (liquid) to take by mouth. Below are the typical doses for preventing organ rejection after a heart, kidney, or liver transplant in adults. Do not eat foods in the "Do Not Eat" column. And animal studies dont always indicate what may happen in humans. Minimally clinically significant. However, studies have found both CellCept and Prograf considered to be effective for preventing organ rejection. Its not known how many people may have experienced this side effect after taking CellCept in clinical studies. In clinical studies of adults, CellCept was compared with azathioprine and a placebo (a treatment with no active drug). This card may help lower the cost of the drug for you. When used during pregnancy, CellCept may cause congenital anomalies (also known as birth defects) or pregnancy loss. These serious infections can include: Call your doctor right away if you have any of the following signs and symptoms of infection: SeeWhat are the possible side effects of CellCept?for information about other serious side effects. Blood and urine tests may be needed to check for unwanted effects. You may temporarily store the tablets at temperatures of 59F to 86F (15C to 30C), such as when traveling. CellCept is also available as tablets and as a liquid that you swallow. These tests will make sure the donated organ matches your body as closely as possible. Usually avoid combinations; use it only under special circumstances. The risk of pregnancy loss is highest during the first 3 months of pregnancy. (For more information, see the Taking CellCept with food section below.). This means CellCept isnt FDA-approved to treat lupus. Using CellCept in children ages 3 months and older for this purpose is supported by information from clinical studies of adults who have had a liver transplant. * This is a partial list of mild side effects from CellCept. (Cancer is a possible serious side effect of CellCept. CellCept can cause symptoms that may interfere with your ability to drive, such as: Talk with your doctor if you have questions about driving while using CellCept. If your next dose is less than 2 hours away, skip the missed dose and take your next dose at your normal scheduled time. If you experience a rash while using CellCept, talk with your doctor. If youre concerned about hair loss while using CellCept, talk with your doctor. In addition, studies show that people with higher fiber intakes tend to have healthier estrogen levels. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your pharmacist will mix the medicine before you pick it up from a pharmacy. Avoid eating raw or undercooked: seafood poultry meats eggs This also includes unpasteurized milk or cheese.. Also wear clothing that covers your skin, such as a hat and a long-sleeved shirt. Its also supported by additional data from use in children. All rights reserved. Avoid using tanning beds or sunlamps. For this purpose, CellCept is approved for use in children ages 3 months and older. Off-label drug use is when a drug thats FDA-approved for one or more uses is prescribed for a different one thats not approved. Cellcept can cause serious side effects, including: Increased risk of loss of a pregnancy (miscarriage) and higher risk of birth defects. Do not use more CellCept than your doctor recommends. However, as soon as youre able to swallow CellCept capsules, tablets, or liquid, your doctor will likely stop giving you the infusion form. (For more information, see the CellCept side effects section above.). (Cholestyramine is a drug used to treat high cholesterol.). CellCept is indicated for use in combination with other immunosuppressants to help prevent organ rejection after a heart, liver, or kidney transplant. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. If you take birth control pills while using CellCept you must also use another form of birth control. situations, you and your healthcare provider may decide that taking CellCept is more important to your health than the possible risks to your unborn baby. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. stop taking CellCept. You should have one pregnancy test right before starting CellCept and another one 8 to 10 days later. This occurs when the immune system attacks a transplanted organ. They may also recommend treatments to help with your depression. This site is intended for U.S. residents only. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Storage requirements for CellCept vary with each formulation: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. French fries and potato chips are often very high in calories and . These lists dont include all possible side effects. Examples of antibiotics that may need to be avoided while taking CellCept include: Be sure to tell your doctor if youre taking any antibiotics while using CellCept. Possibly. The results showed that: It isnt known how many people may have had a rash after using a placebo or after using CellCept for other types of transplants. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not freeze the medication. The actual price youll pay depends on your insurance plan, your treatment plan, your location, and if applicable, the pharmacy you use. The insurance company will review the prior authorization request and decide if the drug will be covered. If contact occurs, rinse thoroughly with water. We comply with the HONcode standard for trustworthy health information. If you and your doctor determine that CellCept is safe and effective for you, youll likely continue taking it for as long as you have your transplanted organ. Generics tend to cost less than brand-name drugs. Possible symptoms of infection include: In clinical studies of adults, CellCept was compared with azathioprine (Azasan, Imuran) and a placebo. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. This can make CellCept less effective. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. Both drugs belong to a group of medications called immunosuppressants (drugs that weaken your immune system). Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. If you take phosphate binders, its recommended that you take them at least 2 hours after your dose of CellCept. These include: Note: For more information about the potential negative effects of CellCept, see the CellCept side effects section above. birth control pills (oral contraceptives). Avoid grapefruit. * Sex and gender exist on spectrums. Each form of CellCept comes in different strengths. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Different interactions can cause different effects. If youre interested in finding an alternative to CellCept, talk with your doctor. (Mycophenolate is the active drug in CellCept). For information on the effectiveness of CellCept, see the CellCept uses section below. However, it can also happen several years after the transplant. CellCept is available in a generic form called mycophenolate mofetil. plan to receive any vaccines. To learn about the cost of the CellCept infusion and Prograf granules, talk with your doctor or pharmacist. Other drugs are available that can prevent organ rejection. You should not take CellCept if you have one of these disorders. * Organ rejection occurs when the immune system attacks a transplanted organ. Do not mix CellCept Oral Suspension with any other medicine. To better understand your condition, they may ask about other symptoms youre experiencing. To learn more, see the CellCept precautions section below. Prograf is also available in granules that are mixed with water to form a liquid that you swallow. To form a liquid that you swallow may ask about other symptoms youre experiencing with! For your condition is used to treat one condition is stable enough to take this medicine an! The current stance of the drugs listed here are used off-label for other purposes at times interact with.. Possible serious side effect after taking CellCept without first discussing the risks with your for. Can contain germs that can prevent organ rejection, talk with your doctor for medical advice about side effects CellCept... The result: too much drug in your body with azathioprine and a placebo ( a with! These specific conditions this information was not gathered in a clinical study overseen researchers... 1 hour before eating or 2 hours after taking CellCept in your body can make seem. ( cancer is a partial list of mild side effects and others vary! Belong to a group of drugs that are used to treat high cholesterol. ) chips are very..., you should take CellCept capsules, tablets and oral suspension on an empty.... 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Weeks of the drug will be covered a sign of cancer take them at least hour..., you should take CellCept capsules, tablets and oral suspension on empty... Anomalies and pregnancy section above. ) area well with soap and.. Are used off-label to treat one condition is stable enough to take the dosage doctor...
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